Authority + 指示 + Recipient + Verb Phrase
指示 (zhǐshì) as a verb means "to instruct," "to direct," or "to order," indicating that someone in authority is giving official guidance or commands to a subordinate. It implies a formal, top-down relationship between the person giving and receiving the instruction. It is commonly followed by a person or organization and then the content of the instruction.
总统指示国务卿立即展开谈判。
Zǒngtǒng zhǐshì guówùqīng lìjí zhǎnkāi tánpàn.
The president instructed the Secretary of State to begin negotiations immediately.
经理指示我们在周五之前提交报告。
Jīnglǐ zhǐshì wǒmen zài zhōuwǔ zhīqián tíjiāo bàogào.
The manager instructed us to submit the report before Friday.
上级指示各部门加强安全检查。
Shàngjí zhǐshì gè bùmén jiāqiáng ānquán jiǎnchá.
The superiors instructed all departments to strengthen security inspections.